Dr Pham Thanh Duy
Pham Thanh Duy
Head of OUCRU Molecular Epidemiology Group
Dr Duy Pham is a Wellcome Trust Fellow and Head of Molecular Epidemiology Group at Oxford University Clinical Research Unit (OUCRU), Ho Chi Minh City, Vietnam. Dr Pham is a molecular biologist and has expertise in genomics and molecular epidemiology of bacterial infections. His research integrates advanced molecular biology and genomics with epidemiological surveillance and clinical study to address drug-resistant bacterial infections in Vietnam and across Asia. He has been working on typhoid fever (S. Typhi and S. Paratyphi A), and diarrheal diseases (i.e. diarrhea-causing E. coli, Shigella spp) since 2008, and have recently expanded his research interests in bloodstream infections (i.e. E. coli, K. pneumoniae), and nosocomial infections (i.e. A. baumanii, K. pneumoniae). His research aims to provide better understanding of the evolution, transmission dynamics, and clinical impact of drug-resistant bacteria in low- and middle-income settings for guiding public health interventions and improving clinical practices.
His current project focuses on combining genomics, RNA sequencing and evolutionary experiments with clinical study to investigate the emergence and impact of azithromycin-resistant Salmonella Typhi, the causative agent of typhoid fever. Additional project includes understanding the impact of antimicrobial exposure on human gut microbiome, horizontal gene transfer, and the development of drug resistance. He is also working on studying the ecology and evolution of hypervirulence and antimicrobial resistance in Klebsiella pneumoniae.
The clinical features and genomic epidemiology of carbapenem-resistant Acinetobacter baumannii infections at a tertiary hospital in Vietnam.
Diep DTH. et al, (2023), Journal of global antimicrobial resistance
A fatal outbreak of neonatal sepsis caused by mcr-10-carrying Enterobacter kobei in a tertiary care hospital in Nepal.
Manandhar S. et al, (2022), The Journal of hospital infection, 125, 60 - 66
Genomic epidemiology, antimicrobial resistance and virulence factors of Enterobacter cloacae complex causing potential community-onset bloodstream infections in a tertiary care hospital of Nepal.
Manandhar S. et al, (2022), JAC-antimicrobial resistance, 4
Prevalence of carbapenem resistance and its potential association with antimicrobial use in humans and animals in rural communities in Vietnam.
Yen NTP. et al, (2022), JAC-antimicrobial resistance, 4
The evolutionary history of Shigella flexneri serotype 6 in Asia
Mai S-NT. et al, (2021), Microbial Genomics, 7