Dr Sophie Uyoga
Sophie trained as a biochemist in Kenya then specialized in Immunology and later obtained a PhD from the University of Heidelberg. Sophie has great interest in understanding how human genetics influences susceptibility to severe malaria. Her work focuses on red blood cell genetic polymorphisms namely hemoglobin S, alpha thalassemia, glucose-6-phosphate dehydrogenase deficiency and blood group antigens and also explores the effect of co-inheritance on protection afforded against severe malaria and other infectious diseases.
A Mid-Career research fellowship awarded by the Initiative to Develop African Research Leaders (IDeAL) has enabled Sophie to pursue another area of interest. She will be investigating the mechanisms behind the development and treatment of severe anemia with focus on the quality of donor blood on recovery from severe anemia and survival post-transfusion. She envisions that the study findings will inform future strategies to ensure efficient provision of services by blood transfusion services and policy makers in Africa.
Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya.
Adetifa IMO. et al, (2021), Nature communications, 12
Pharmacokinetics and pharmacodynamics of azithromycin in severe malaria bacterial co-infection in African children (TABS-PKPD): a protocol for a Phase II randomised controlled trial
Olupot-Olupot P. et al, (2021), Wellcome Open Research, 6, 161 - 161
Point-of-care haemoglobin testing in African hospitals: a neglected essential diagnostic test.
Uyoga S. et al, (2021), British journal of haematology, 193, 894 - 901
Revealing the extent of the first wave of the COVID-19 pandemic in Kenya based on serological and PCR-test data
Ojal J. et al, (2021), Wellcome Open Research, 6, 127 - 127
Transfusion management of severe anaemia in African children: a consensus algorithm
Maitland K. et al, (2021), British Journal of Haematology