Dr Thomas Lamb
Contact information
Thomas Lamb
Snake Bite Coordinator
Thomas Lamb is a project coordinator for antivenom research at MOCRU and the 1st Hamish Ogston Foundation Fellow. His prior clinical experience with snake-bite envenoming in India, Bangladesh and UK has resulted in a desire to improve antivenom availability and affordability to those who need it most in a timely manner.
Snake bite in Myanmar is the leading cause of acute kidney injury requiring dialysis and is estimated to cause 1,250 death/year. The principal objective of this work is to conduct a dose-finding study of a novel lyophilized Daboia siamensis antivenom produced in Myanmar. The optimal dose will seek to reverse the effects of venom in a single dose whilst limiting the incidence of severe adverse reactions. In addition to the dose-finding trial, we plan to investigate snake-bite diagnostics including the 20-minute whole blood clotting test, perform a pharmacokinetic assessment of venom in humans and describe the Daboia siamensis envenoming sequelae.
Recent publications
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Lessons from the field: compound-specific management in acute pesticide poisoning.
Verma VR. et al, (2024), Transactions of the Royal Society of Tropical Medicine and Hygiene, 118, 347 - 349
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Assessment and management of secondary bacterial infections complicating Mpox (Monkeypox) using a telemedicine service. A prospective cohort study.
Moody S. et al, (2023), International journal of STD & AIDS, 34, 434 - 438
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Comment on Glatstein's case series of Echis coloratus envenoming in children.
Lamb T. and Eddleston M., (2022), Clinical toxicology (Philadelphia, Pa.), 60, 661 - 662
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Moderate-to-severe Vipera berus envenoming requiring ViperaTAb antivenom therapy in the UK.
Lamb T. et al, (2021), Clinical toxicology (Philadelphia, Pa.), 59, 992 - 1001
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The 20-minute whole blood clotting test (20WBCT) for snakebite coagulopathy—A systematic review and meta-analysis of diagnostic test accuracy
Lamb T. et al, (2021), PLOS Neglected Tropical Diseases, 15, e0009657 - e0009657