Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Researchers from the Oxford University Clinical Research Unit in Vietnam have completed what is probably the largest ever controlled trial of tuberculous meningitis. The study is published in the New England Journal of Medicine.

CTMGH logo for News

Researchers from the Oxford University Clinical Research Unit in Vietnam have completed what is probably the largest ever controlled trial of tuberculous meningitis. The study is published in the New England Journal of Medicine

Tuberculous meningitis is the most destructive form of the disease, with tuberculosis bacteria infecting the thin sheaths covering the central nervous system, resuling in fever and headaches. One third of infected patients die, despite current treatment. 

Guy Thwaites and his colleagues therefore tested whether an intensified antituberculosis treatment (higher doses of a currently used antibiotic, rifampin, combined with another antibiotic, levofloxacin) might help improve survival rates.

Similar stories

Picturing Health: The Burden of Leprosy in Eastern Indonesia

The Eijkman Oxford Clinical Research Unit in Indonesia and Sumba Foundation collaborated with photographer Yoppy Pieter to express the human face of leprosy in Sumba, a remote island in eastern Indonesia. The project aimed to visualize the story of leprosy and raise awareness of this debilitating and heavily stigmatised disease

Research Culture at OUCRU

What do we mean by 'Research Culture' and how has fostering a multinational, collaborative culture helped us deliver world-class research? Let's explore the research culture at OUCRU.

Policy and Public Engagement at OUCRU

Why does OUCRU place an important focus on engaging with its important partners, policy makers, the press, the community, and young people? Explore our work in policy & public engagement.

World TB Day 2022: Invest to End TB. Save Lives

Each year on 24 March, World TB Day is commemorated to raise awareness of this devastating and deadly disease. The theme for this year’s World TB Day is “Invest to End TB. Save Lives”, conveying the urgent need to invest resources to ramp up the fight against TB and achieve the commitments to end TB made by global leaders.

TACT-CV study shows artemether–lumefantrine plus amodiaquine an effective treatment for multidrug-resistant malaria in GMS

A triple artemisinin-based combination therapy (TACT) of artemether-lumefantrine plus amodiaquine (AL+AQ) for uncomplicated falciparum malaria in areas with a high prevalence of artemisinin resistance is a well-tolerated, effective treatment for multidrug-resistant parasites, say a team of MORU-led researchers.

OUCRU Research Themes and Future

In this video, explore OUCRU's research areas and what questions we are aiming to answer in the next 5 years.