Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

The world’s largest clinical trial investigating treatments for COVID-19 has now launched in Ghana, West Africa. This is the sixth country to take part in RECOVERY, joining Indonesia, Nepal, South Africa, Vietnam, and the United Kingdom.

Aerial image of town in Ghana

Since March 2020, the RECOVERY Trial has discovered three effective treatments for COVID-19: the inexpensive steroid dexamethasonethe arthritis drug tocilizumab; and a monoclonal antibody treatment, now known as Ronapreve. However, as the pandemic continues to affect both high and lower income countries, and with the constant threat of new coronavirus variants, treatments are needed that are suitable for a wide range of patients and healthcare systems. Consequently, RECOVERY International was launched in February 2021.

Professor Sir Peter Horby, Joint Chief Investigator of RECOVERY, said: ‘I am thrilled to welcome Ghana to the RECOVERY endeavour to improve the care of patients with severe COVID-19. COVID-19 affects everyone, and we need treatments for everyone, wherever they are and whatever level of healthcare is available to them.’ 

In Ghana, RECOVERY will initially focus on whether using a higher dose of the anti-inflammatory treatment dexamethasone has an even greater effect than the standard doses of the drug previously shown to save lives by the RECOVERY trial. It is likely that empagliflozin, a routine treatment for type 2 diabetes, will also be added to the study in Ghana soon.

The first Ghanaian hospitals taking part in RECOVERY are the Ghana Infectious Disease Centre, Accra, and the Komfo Anokye Teaching Hospital, Kumasi. The study will be open to all hospital patients admitted with confirmed COVID-19. All participants will receive the usual care; some will additionally receive one of the treatments being investigated.

The expansion of RECOVERY International to Ghana is a partnership between the University of Oxford and the Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR).

The full story is available on the RECOVERY website

Similar stories

Field evaluation of EasyScan GO: a digital malaria microscopy device

Microscopic examination of Giemsa-stained blood films is key to quantifying and detecting malaria parasites but there can be difficulties in ensuring both a high-quality manual reading and inter-reader reliability. The EasyScan GO was developed as a potential solution to this, a microscopy device using machine-learning-based image analysis for automated parasite detection and quantification.

Registration is open for The Global Health Network Conference 2022

To tackle disease we need evidence to be generated through every type of health research study. This conference aims to bring together health research teams, organisations, health-workers, policy makers and practitioners to explore together how health research can be embedded into every healthcare setting. Join us at The Global Health Network Conference 2022 at the University of Cape Town, South Africa, 24 – 25 November 2022

The inside story of Recovery: how the world’s largest COVID-19 trial transformed treatment – and what it could do for other diseases

Two years ago, the Recovery trial transformed the care of COVID patients with its dexamethasone announcement. Within four hours, the steroid was included in NHS treatment recommendations. Almost overnight, treatment of COVID patients around the world changed completely. It has been estimated that dexamethasone may have saved a million lives in the first nine months following the announcement. Recovery is a groundbreaking scientific machine which, from the outset, moved at unprecedented speed. In the first 100 days alone, the trial produced three groundbreaking results that would completely reshape COVID care.

Gail Carson chair of GOARN

Dr Gail Carson from the International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) is nominated chair of WHO Global Outbreak Alert & Response Network (GOARN)

RECOVERY trial celebrates two-year anniversary of life-saving dexamethasone result

Two years ago, the RECOVERY trial gave the world its first breakthrough against coronavirus: the discovery that an inexpensive steroid pill, dexamethasone, reduced deaths by up to a third from COVID-1. Within hours, the result was breaking news across the world and hospitals were adopting the drug into the standard care given to all patients with COVID-19. In the nine months following the discovery, dexamethasone saved an estimated one million lives worldwide.

Congratulations to Professor Sir David Warrell, appointed Knight Commander of the Order of St Michael and St George!

David Warrell, MORU founding director, has been appointed by the Queen ‘Knight Commander of the Order of St Michael and St George for services to global Health Research and Clinical Practice’. Please join us in congratulating Sir David on receiving this richly deserved high honour!