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Simon Mendelsohn (cohort 2015-16) co-authored this systematic review protocol on the current triage and predictive tools and how host tuberculosis transcriptomic biomarkers may be more effective for a correct diagnosis.

Current tuberculosis triage and predictive tools offer poor accuracy and are ineffective for detecting asymptomatic disease in people living with HIV (PLHIV). Host tuberculosis transcriptomic biomarkers hold promise for diagnosing prevalent and predicting progression to incident tuberculosis and guiding further investigation, preventive therapy and follow-up. We aim to conduct a systematic review of performance of transcriptomic signatures of tuberculosis in PLHIV.

Read the full study on BMJ Open.