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What are the health and socio-economic impacts of physical distancing in African countries and how can they be mitigated? This work by Edwine Barasa and colleagues reviews the effects of physical distancing restrictions and recommends that African countries need to consider the broader net benefit of measures that they choose to implement and to adapt and localize their response to align with the contextual realities of the continent, and to optimize expected benefits of physical distancing, while minimizing the undesired impacts.

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We gathered rich insights into child survival in Kenya by mapping patterns over 22 years

Although improvements in child survival globally have been remarkable, 5.2 million children still died in 2019, over half of these in sub-Saharan Africa. A range of factors likely include disparities in childhood immunisations, supplements and breastfeeding practices, antenatal care, skilled birth attendants working in healthcare facilities. Kenya needs to prioritise its child care plans, based on localities and populations with the greatest need. Two KWTRP studies give granular insights into the situation in regions across Kenya.

What it takes to reach zero malaria

Interview with KWTRP Malaria immunologist Dr Francis Ndungu. Francis grew up in central Kenya where malaria is not prevalent but is interested in understanding of how semi-immune individuals control malaria parasite growth and the associated inflammation symptoms. His current work is in understanding how we develop immunity to Malaria. He is also interested in the potential translation of that knowledge in the development of effective malaria vaccines.

Celebrating women in ICT: connected girls, creating brighter futures

The International Girl’s in ICT day is commemorated to create awareness on the critical need for more girls and women in the ICT sector, encourage and inspire young girls to actively pursue careers in STEM as well as engage the community to promote collaboration through partnerships. Kathreen Wafula, an ICT Support Technician in Kilifi, joins a strong team of techies and is one of the 4 women in the department.

Risks of serious adverse events following treatment for visceral leishmaniasis

This large-scale systematic review and meta-analysis aimed to collate all reported serious adverse events in visceral leishmaniasis clinical trials and quantify the incidence of mortality during the first 30 days of therapy. The analyses, which included clinical data from more than 35,000 patients, found that mortality following treatment was an extremely rare event and serious adverse events following treatments were poorly reported.

Researchers call for access to Ivermectin for young children

Millions of children weighing less than 15kg are currently denied access to Ivermectin treatment due to insufficient safety data being available to support a change to the current label indication. The WorldWide Antimalarial Resistance Network’s new meta-analysis provides evidence that supports removing this barrier and improving treatment equity.

Gender imbalance in visceral leishmaniasis clinical trials

Researchers have found that despite an ongoing trend for a decreasing proportion of males being enrolled in antileishmanial therapeutic efficacy trials over time, there are still 1.8 times as many males as females involved in clinical trials. A new systematic review and meta-analysis suggests that existing knowledge on drug efficacy is derived from a study population that is heavily skewed towards adult males. At the same time, substantially less is known about the optimal treatment response in female patients.