Dr Bob Taylor
Senior Clinical Research Fellow
Dr Bob Taylor works on drug trials for vivax and falciparum malaria. In contrast with falciparum malaria, vivax malaria can relapse from dormant stage parasites in the patient’s liver. Primaquine is currently the only available drug to prevent relapse infections but can cause severe haemolysis in patients with reduced G6PD activity. Dr Taylor's research aims to determine the most effective and safest way to radically cure vivax malaria.
Primaquine can be used both to treat vivax malaria and to prevent the transmission of falciparum malaria from human to mosquito. A shorter and age-based primaquine regimen would reduce the burden of vivax malaria. It would also allow primaquine to be used more widely to block the transmission of falciparum malaria.
Taylor A. et al, (2018), BMC Research Notes, 11
Thriemer K. et al, (2018), Malaria Journal, 17
Taylor WR. et al, (2018), BMC Medicine, 16
Ghatee MA. et al, (2018), Parasitology Research, 117, 3447 - 3458
Commons RJ. et al, (2018), The Lancet Infectious Diseases, 18, 1025 - 1034