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Ruan Spies

Ruan Spies

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Ruan Spies

DPhil Student


  • MSc Global Health Science and Epidemiology, University of Oxford 2023
  • Medicine, University of Cape Town 2019


  • Community Service Medical Officer (Senior House Officer), New Somerset Hospital, Cape Town, South Africa  Jan 2022– Oct 2022
  • Intern Medical Doctor (Foundation Year equivalent), Livingstone Hospital Complex, Gqeberha, South Africa   Jan 2020 – Dec 2021


  • How do people get drug-resistant tuberculosis?
    People with drug-resistant TB can have acquired their disease in one of two ways: from others through direct transmission or through the selection of drug resistance mutations while receiving first-line TB therapy. Empiric evidence describing the relative contributions of each mechanism to the current burden of drug-resistant in Ho Chi Minh City, Vietnam is lacking.
    My project uses whole genome sequencing-derived data to describe TB transmission in Ho Chi Minh City and to infer the relative contributions of transmitted and selected resistance to drug-resistant TB in the city. This may have important implications for public health TB control measures.