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Kathmandu, the capital city of Nepal, has been previously coined an enteric fever capital of the world. Several studies have poignantly emphasized the significant burden of enteric fever within the local population and in travellers visiting the area. The population of Kathmandu is increasing and available figures suggest that enteric fever caused by Salmonella serovars Typhi and Paratyphi A show no significant signs of decreasing. Furthermore, our recent research demonstrates that the ratio of disease caused by these two organisms is shifting towards S. Paratyphi A. Here, we outline some of the major features of enteric fever in Kathmandu, including diagnosis, seasonal variation, transmission, and some characteristics of the infecting organisms. Our findings highlight the requirement for better understanding of the disease within the city; in turn, this will aid development of a targeted control strategy.

Original publication

DOI

10.3855/jidc.162

Type

Journal

Journal of infection in developing countries

Publication Date

12/2008

Volume

2

Pages

461 - 465

Addresses

Oxford University Clinical Research Unit, Patan Hospital, Lagankhel, Lalitpur, Bagmati, Kathmandu, Nepal.

Keywords

Humans, Salmonella paratyphi A, Salmonella typhi, Typhoid Fever, Public Health, Seasons, Geography, Nepal