16 October 2019
When we are ill, we trust that the medicines that we take will make us feel and be better. But what if our pills do not contain the ingredients listed on the packaging? The art exhibition ‘What’s in your medicines?’ explores how substandard and falsified (‘fake’) medicines can affect our health, by showcasing the striking and original artwork of 12 South East Asian artists.
Pearl Gan, photographer in residence at OUCRU in Vietnam and EOCRU in Indonesia wins FIGO's 2019 photo competition
16 October 2019
A mother and her baby leave a Puskesmas - a government-mandated primary care clinic - in West Java, Indonesia, following a check-up. The woman smiles, as the infant stares out from the safety of a bright sarong wrap. This quiet moment of active participation in their own health and well-being is the realisation of a fundamental human right. WHO’s vision for primary health care in the 21st century is to ensure the highest possible level of health and well-being, with equitable distribution.
9 October 2019
Oxford Medical Sciences Divisional Panel has conferred the title of Professor on three members of our Centre. Ben Cooper - Professor of Epidemiology, Sassy Molyneux - Professor of Global Health and Piero Olliaro - Professor of Poverty Related Infectious Diseases were awarded these titles in recognition of their distinction in their respective fields and contributions to the research, teaching and administration of the Department and we congratulate them on their success!
New research supports co-administration of primaquine with artemisinin-based combination therapies for P. vivax malaria
8 October 2019
An individual patient data meta-analysis of 2,017 patients from 19 studies has found a high risk of recurrence following treatment of P. vivax malaria with artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) unless they are co-administered with primaquine. The research supports recommendations that these artemisinin-based combination therapies (ACT) should be combined with primaquine.
8 October 2019
The Africa Oxford Initiative (AfOx) is a cross-university network that brings the University of Oxford’s long-standing, multi-disciplinary engagement with Africa under one platform. The overarching goal of AfOx is to ensure Africa remains a strategic priority for the University, and that students and academics who attend from the Continent feel supported and at home while they are here.
7 October 2019
Professor Sir Peter J Ratcliffe, Director for the Target Discovery Institute within the Nuffield Department of Medicine at Oxford University and Director of Clinical Research at Francis Crick Institute, London, has today been announced as a winner of the Nobel Prize in Physiology or Medicine.
4 October 2019
The Oxford based OHSCAR team is delighted to be a partner the NEST360 project working with KEMRI-Wellcome and the Kenya Paediatric Research Consortium in Kenya to support this effort to improve care care of the sick newborn and save lives
1 October 2019
Oxford University is running a campaign to celebrate Black History Month. Throughout October the university will amplify the annual celebration with a series of content streams and events recognising and appreciating the contributions that BME communities make to society and the university itself. From academics to students, staff and alumni, the campaign will shine a light on black people’s achievements, and echo the growing call for inclusion in all areas of life from education to cultural appreciation.
18 September 2019
MORU and SMRU were delighted and honoured to host the University of Oxford Vice-Chancellor Prof Louise Richardson and her party during her visit to Thailand on 1-4 September. Accompanying the Vice-Chancellor were Jeremy Woodall (Director of Development (Asia)), Frewyeni Kidane (Fundraiser for Southeast Asia), Cher Wu (Asia Development office) and Ed Gibbs (NDM Director of Finance and Operations).
18 September 2019
This report presents research on the current state of governance and coordination of health emergency preparedness and response. It highlights key challenges to address for the future. The report was commissioned by the Global Preparedness Monitoring Board to inform their inaugural report launched on 18th September 2019.
18 September 2019
In partnership with the Wellcome Innovations Flagship Programme, MORU launched its Critical Care Asia Network project with its first investigators’ meeting on 19-20 Aug in Bangkok. The project will establish an Asian ICU network across 42 ICUs in nine countries and implement a setting-adapted electronic registry.
17 September 2019
Two researchers from the Centre for Tropical Medicine and Global Health were awarded medals by the Royal Society of Tropical Medicine and Hygiene at the 2019 European Congress on Tropical Medicine and International Health. Professor David Warrell was awarded the Sir Patrick Manson Medal, and Dr Samson Kinyanjui the Chalmers Medal.
13 September 2019
In Kenya, the poorest of the poor carry the highest burden of disease. From locally-made, low-cost herbal remedies to affordable hard floors for households, researchers and communities are developing new ways to deal with jiggers in Kenya. Lynne Elson, a research fellow at KEMRI Wellcome Trust, lead a study to determine whether neem and coconut oil reduce inflammation, pain and itching better than the standard treatment in seven days.
11 September 2019
Oxford has been named the world’s number one university for the fourth successive year in the Times Higher Education World University Rankings.
8 September 2019
Human trials of new antimalarial drugs are in the pipeline after KEMRI scientists successfully used bacteria to kill the parasite that causes the disease. Trials in Burkina Faso showed that Ivermectin, a conventional drug used for parasitic diseases including river blindness and elephantiasis, reduced transmission rates. The medication worked by making the blood of people who were repeatedly vaccinated lethal to mosquitoes. The study also found that Ivermectin can kill plasmodium falciparum, the malaria parasite carried by female mosquitoes, when administered to humans.
27 August 2019
The provision of high-quality care to sick newborns presents challenges in any health system. International guidelines suggest that even for babies who do not require intensive care, there should be one nurse for every 2 – 4 sick babies. However, recent studies conducted in Nairobi show that one nurse takes care of between 20 – 40 newborns. In a recently published policy brief the KEMRI Wellcome Trust programme highlights the experience of nurses in Nairobi’s New Born Units.
7 August 2019
IDDO has launched a new global Chagas scientific collaboration with the Drugs for Neglected Diseases initiative (DNDi). The new platform will collate and standardise data to accelerate better treatments for the 6–7 million people worldwide with Chagas disease.
1 August 2019
The Nairobi Programme at KEMRI Wellcome Trust Research Programme hosts over 17 principal researchers, 15 PhD fellows and a dedicated team of over 40 research assistants spanning clinical research, health services research, population health research, and health systems and economics research. Learn more about the ongoing research and the principal researchers behind the work.
Latest research finds primaquine improves haemoglobin by day 42 following treatment of P. vivax malaria
1 August 2019
An IDDO/WWARN study has found that primaquine is not associated with increased levels of anaemia following treatment of patients without G6PD deficiency for P. vivax malaria and should be used as part of a radical cure. In the largest study of its kind to date, researchers carried out a systematic review and individual patient data meta-analysis which involved 3,421 patients in 29 studies published in BMC Medicine.
Better Research for Better Health: University of Oxford and Fiocruz partner to improve health research and capacity development globally
31 July 2019
A new strategic partnership between Fiocruz and The Global Health Network will amplify the impact of Fiocruz’s health research and capacity development initiatives by promoting research capacity building across Portuguese-speaking countries, and enabling research findings from the Zika outbreak to benefit public health worldwide.
25 July 2019
KWTRP has launched a dataset of comprehensive public health facilities from 50 countries in sub- Saharan Africa. This new dataset locates health facilities in relation to the communities they are intended to serve, to help ensure that services are accessible to the right populations and that no one is geographically marginalized from essential services. This is critical for attainment of Sustainable Development Goal 3 on good health and wellbeing.
24 July 2019
MORU researchers have found that severe malnutrition is associated with lower exposure to the antimalarial drug lumefantrine in children treated with artemether-lumefantrine, the most common treatment for uncomplicated falciparum malaria. The study, which is the first to specifically address this, calls urgently for further research into optimised dosing regimens for undernourished children.
Rapidly spreading multidrug-resistant parasites render frontline malaria drug ineffective in southeast Asia
23 July 2019
The findings of two studies, published in The Lancet Infectious Diseases journal, reveal that by 2016–2018 malaria parasites resistant to both artemisinin and its widely used partner drug piperaquine represented more than 80% of the parasites circulating in northeast Thailand and Vietnam, despite having only emerged in western Cambodia in 2008.
19 July 2019
A large clinical trial in Africa and Asia has shown that a 7 day course of high dose primaquine, a drug used to treat P. vivax malaria, is well tolerated and just as effective as the current standard 14 day regimen, according to a study published this week in The Lancet. These findings have important implications for the treatment and elimination of vivax malaria in the Asia Pacific.
17 July 2019
Medical Action Myanmar and MOCRU health teams identified a number of children with rickets in remote areas of Myanmar. MOCRU director Frank Smithuis presented the findings of clinical screening to the Minister of Health, alongside treatment results and a plan for a large survey to investigate the prevalence of vitamin D deficiency and its underlying causes.
Bringing science and health research to Kenyan schools project wins University Public Engagement with Research Award
10 July 2019
A project bringing science to Kenyan schools, led by Dr Alun Davis from Kemri Wellcome Trust Research Programme in Kenya and Nuffield Department of Medicine, has won a Project Award in this year’s Vice-Chancellor’s Public Engagement with Research Awards.
10 July 2019
A project using drama that engages with village communities in Cambodia, led by Professor Phaik Yeong Cheah of the Mahidol Oxford Tropical Medicine Research Unit and Nuffield Department of Medicine, has won a Project award in this year’s Vice-Chancellor’s Public Engagement with Research Awards. The project also won the Vice-Chancellor’s Choice Award for Public Engagement with Research.
2 July 2019
New research by Makoto Saito and colleagues at SMRU found that a longer follow-up is required to assess antimalarial drug efficacy in pregnant women. This was found across all drugs assessed in low malaria transmission settings. The report’s authors have called for guidelines specifically for pregnant women and further investigation of optimal follow-up periods in high malaria transmission settings.
28 June 2019
IDDO’s visceral leishmaniasis (VL) collaboration is working on two new projects looking at the treatment of VL. The first is a systematic review of the literature on design and analysis of antileishmanial clinical efficacy studies, and the second is a systematic review of published studies to estimate the baseline risk of serious adverse events and mortality in patients treated with antileishmanial therapies.
14 June 2019
WWARN Researcher Debashish Das has been involved in clinical research in various settings in Asia and Africa with the Mahidol-Oxford Tropical Medicine Research Unit (MORU) and Médecins Sans Frontières (MSF). His research efforts focus on investigating antimalarial drug resistance and finding treatment solutions for young children
12 June 2019
A workshop held in Dakar, Senegal, 7-18 March, highlighted the need for better community engagement during global health emergencies. An international group of experts in community engagement for health research identified urgent measures to foster involvement of local communities in emergency research, such as the Ebola outbreak in Democratic Republic of Congo.
12 June 2019
A ground-breaking study in Bangladesh co-lead by MORU has found that using data from mobile phone networks to track the movement of people across the country can help predict where outbreaks of diseases such as malaria are likely to occur, enabling health authorities to take preventative measures.
5 June 2019
WWARN’s Clinical Scientific Group have published research in BMC Medical Research Methodology comparing different statistical approaches for deriving cumulative estimates of drug efficacy from clinical studies. Results indicate that the Cumulative Incidence Function (CIF) approach should be considered as an alternative to the widely used Kaplan-Meier method for calculating efficacy estimates in high transmission areas.
4 June 2019
MORU, SMRU and FilmAid Foundation invite you to the Bangkok Premiere of Under the Mask on the 17th June. This drama film is based on real testimonies of TB patients. The story follows the lives of our characters as they journey from diagnosis to treatment and help from the SMRU TB team, and explores how each discovers their capacity to overcome the deadly disease and share their knowledge and experience with others. Made in the local language, this film provides an engaging and inspiring tool for raising TB awareness in the community.
24 May 2019
Avni Gupta, Communications Officer for AfOx, talks about the work of this university-wide initiative – which brings the University’s long-standing multi-disciplinary engagement with Africa under one platform
24 May 2019
In this letter co-signed by Peter Horby and Vicki Marsh, researchers stress the importance of building trusting relationships with communities affected by ebola. As shown in DRC, trust is not a given, which is one of the reasons why community engagement – involving local people in the development of the response from the very start – is so important. In conflict zones this is more difficult than in other emergencies, and yet even more important.
17 May 2019
IDDO Ebola Data Platform, a pioneering collaboration in Ebola and emerging infections, has today appointed nine members for its first Data Access Committee, overseen and chaired by TDR, the Special Programme for Research and Training in Tropical Diseases, hosted at WHO.
10 May 2019
This year, the Pint of Science festival in Thailand is in not one but two cities! Join us in Bangkok at WeLearn on 21st-22nd May, and at Hungry Wolf's in Chiang Rai on 25th May.
10 May 2019
The 5th May is World Hand Hygiene Day. To raise awareness among staff and the Thai-Myanmar border populations of the importance of hand washing, a simple, proven effective way of infection prevention, the SMRU infection control committee worked with the SMRU clinics and Mae Sot lab staff to create this fantastic video.
8 May 2019
The Academy of Medical Sciences has elected 50 UK leading figures in biomedical and health sciences to their esteemed Fellowship. Philip Bejon, Director of our Kemri Wellcome Trust Research Programme, and Ric Price, Professor of Global Health at Menzies, Australia and affiliated with OUCRU, are new fellows.
7 May 2019
How to change urban Myanmar communities' antibiotics usage habits? Check out 'Fever and Antibiotic Use', a Wellcome-funded community theatre initiative by MOCRU Research Coordinator Dr Myo Maung Maung Swe. Myo uses forum theatre to engage Yangon residents in a lively manner so they can learn when to use antibiotics – or not.
7 May 2019
Rift Valley Fever, one of WHO priority diseases, causes abortion and malformation in livestock, as well as occasionally severe symptoms in humans. George Warimwe and colleagues at KWTRP are developing a vaccine suitable for both humans and livestock. This cross-species approach, known as “One Health”, might in the long term accelerate the design and development of vaccines, protecting human health and biodiversity too.
3 May 2019
This 5-day course is aimed at participants with a basic understanding of infectious disease modelling and an aptitude for the R programming language. On completion participants will be able to write and analyse the dynamics of a simple mathematical model and use it to consider cost and intervention scenarios. September 23-27 at St Anne’s College, Oxford
30 April 2019
To mark World Malaria Day on 25 April WWARN’s Dr Makoto Saito and Professor Joel Tarning from the Mahidol Oxford Tropical Medicine Research Unit and Head of WWARN Pharmacometrics presented their work on prevention and treatment of malaria in vulnerable groups at a seminar hosted by the Centre for Tropical Medicine and Global Health
30 April 2019
The attainment of Universal Health Coverage (UHC) is a policy priority at both global and national levels. The Sustainable Development Goals underscore the importance of health and wellbeing for all with three main objectives: equity in access to health services, access to quality health services, and protection from financial risk. In Kenya, although the government has installed UHC as a policy priority, it is still marred in misconstruction and often reduced to health financing. Researchers at KEMRI-Wellcome tracked Kenya’s progress towards UHC between 2003 and 2014 and set out recommendations to support policy makers in designing a body of UHC policy.
30 April 2019
Malaria is a leading cause of death and illness around the world. Over 200 million cases are reported every year, and more than 400 000 people die. More than 90% of cases are reported in sub-Saharan Africa. Scientists have spent decades searching for an effective vaccine. Hence the recent excitement when Malawi’s government announced it had launched a pilot programme for the world’s first malaria vaccine, RTS,S (also known as Mosquirix©), produced by the pharmaceutical company, GSK. It’s the first vaccine to demonstrate significant reduction in malaria in children. The Conversation Africa’s Ina Skosana asked immunologist Faith Osier about RTS,S.
25 April 2019
Increased funding is needed to eliminate malaria across 22 Asia-Pacific countries and save an estimated 400,000 lives, according to research published in a new collection of studies on Wellcome Open Research.
25 April 2019
Today April 25 is World Malaria Day. We would like to highlight a malaria photography project by photographer Pearl Gan, in collaboration with OUCRU in Vietnam and EOCRU in Indonesia. Pearl's malaria project aims to bring visibility to the people and their malaria burden through her photographs of them and their environment. She hopes to humanise the faces of malaria and the malaria problem in the Asia-Pacific to audiences unfamiliar with it.
11 April 2019
The Life-saving Instruction for Emergencies (LIFE) is a 3D simulation training app for smartphones that teaches healthcare workers how to manage medical emergencies. LIFE is a scenario-based mobile and virtual reality (VR) gaming platform that teaches healthcare workers to identify and manage medical emergencies using game-like training techniques to reinforce the key steps that need to be performed in order to save lives.